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Extradural Analgesia in Obstetrics – A Controlled Trial of Carbonated Lignocaine & Bupivicane HCL With or Without Adrenaline

D. D. Moir, P. J. Slater, J. Thorburn, R. McLaren, J. Moodie: Extradural Analgesia in Obstetrics – A Controlled Trial of Carbonated Lignocaine & Bupivicane HCL With or Without Adrenaline. British Journal Anaesth. 48, 2, 129-135 Feb 1976.

ABSTRACT

Four local anaesthetic solutions (2% carbonated lignocaine with or without adrenaline and 0.5% bupivacaine HCl with or without adrenaline) were used randomly for 335 continuous lumbar extradural blocks in labour. Carbonated lignocaine caused a more rapid onset of analgesia than bupivacaine HCl. The addition of adrenaline made little difference to the onset times, prolonged markedly the duration of analgesia with carbonated lignocaine and had little effect on the duration of analgesia with…

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