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Intranasal Ketorolac for the Treatment of Postoperative Pain (2007)

Intranasal Ketorolac for the Treatment of Postoperative Pain

Presented at the 2007 American Association of Anesthesiologists Annual Meeting

Intranasal Ketorolac for the Treatment of Postoperative Pain John Moodie, Colin Brown, Eileen Bisley, Lincoln Bynum, Waikato Clinical Research, Hamilton, New Zealand; ICON Clinical Research, Redwood City, California

Ketorolac tromethamine is a water soluble, nonsteroidal, anti-inflammatory drug (NSAID) with potent analgesic and moderate anti-inflammatory activity (1, 2). The parenteral formulation is used IM or IV for the treatment of moderate to severe pain. The analgesic efficacy of ketorolac has been extensively evaluated in the postoperative setting, in both hospital inpatients and outpatients, and in patients with various other acute pain states. Ketorolac has been reported to provide relief from moderate to severe pain in a majority of patients and has similar analgesic efficacy to that of standard doses of morphine and meperidine.

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